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The latest news, stories and exciting findings from across the Oxford cancer research community

University's RadCam library highlighted in yellow

Unique Clinical Imaging Dataset Released for Artificial Intelligence Research to Accelerate Diagnosis of Prostate Cancer

The National Cancer Imaging Translational Accelerator (NCITA) in partnership with the ReIMAGINE Consortium have announced the release of a unique clinical imaging dataset from the Prostate MRI Imaging Study (PROMIS)).

Researchers describe how cancer cells can defend themselves from the consequences of certain genetic defects

Swietach Group scientists have identified a rescue mechanism that allows cancers to overcome the consequences of inactivating mutations in critically important genes

CRUK funding to investigate the molecular drivers of stomach cancer

Dr Francesco Boccellato wins a CRUK Early Detection and Diagnosis primer award to study tissue shape changes in the pre-cancerous stomach conditions, atrophic gastritis and intestinal metaplasia

DPhil in Cancer Science: A medical student's perspective

In this blog, current MB-DPhil student Holly shares her experience of intercalating a DPhil within her medical undergraduate qualification

Genetic mapping of tumours reveals how cancers grow

Researchers from the University of Oxford, KTH Royal Institute of Technology, Science for Life Laboratory, and the Karolinska Institutet, Solna, Sweden, have found that individual prostate tumours contain a previously unknown range of genetic variation.

First patient diagnosed earlier using liquid biopsy technology as part of the AI-REAL programme in sub-Saharan Africa

The AI-REAL programme led by Professor Anna Schuh and research teams in Tanzania and Uganda is improving the early detection and outcomes of childhood lymphoma in the region by increasing the speed and precision of diagnosis.

Tool to detect cancer stem cell make-up in intestinal tumours

The Leedham lab have developed a new tool that assesses the relative enrichment of two main types of cancer stem cells in colorectal cancer, which may help to guide therapy selection in the future.

Measured weight loss associates with an increased risk of a cancer diagnosis

Weight loss is a sign of undiagnosed cancer regardless of the interval over which it occurs.

Comparing polygenic risk scores for risk prediction in individuals

Substantial disagreement in individual risk prediction was found between different polygenic risk scores for breast cancer, hypertension and dementia using genotyping data from the UK Biobank.

Cancer patients remain at higher risk of severe COVID-19 disease despite third dose booster vaccine

A large population-level assessment reveals third dose COVID-19 vaccination is effective for most patients with cancer, but effectiveness is lower than in the general population, particularly in patients who have undergone recent chemotherapy and those with lymphoma.

Oxford Cancer researchers elected to the European Molecular Biology Organization

Congratulations to Ivan Ahel, Adrian Hill and Yang Shi on their election to the membership of the European Molecular Biology Organization (EMBO)

Time-varying nature of clinical risk factors for pancreatic cancer may aid earlier diagnosis

Body mass index, blood tests, comorbidities and medication use are temporally associated with cancer risk in the three years before a pancreatic cancer diagnosis.

Largest study to date confirms role of two hormones in aggressive prostate cancer risk

New, genetics and blood-based study links testosterone and insulin-like growth factor hormones to aggressive prostate cancer for the first time.

National clinical study launched to test new technologies for detecting liver cancer

The SELINA study will recruit patients with early liver cancers as part of the DeLIVER programme aiming to detect liver cancer earlier.

Population-scale study highlights ongoing risk of COVID-19 in some cancer patients despite vaccination

COVID-19 vaccination is effective in most cancer patients, but the level of protection against COVID-19 infection, hospitalisation and death offered by the vaccine is less than in the general population and vaccine effectiveness wanes more quickly.

Early detection innovation award for Oxford researchers

Professor Julia Hippisley-Cox and Dr Tingting Zhu win funding for their collaborative project on novel test technologies for patient triage in primary care.

Dairy products linked to increased risk of cancer

The first major study to investigate dairy consumption and cancer risk in Chinese adults found that greater intake was associated with higher risks of liver cancer and female breast cancer.

Greater adiposity linked to increased risk of fatal prostate cancer

A new Oxford study finds that greater body fat (adiposity) may increase the risk of dying from prostate cancer by up to 10%.

12 new Development Fund awardees

The awardees from the 2021 round of the CRUK Oxford Centre Development fund have been announced. Read about what research they will be undertaking.

Predicting early recurrence of pancreatic cancer

Dr Daniel Hughes and colleagues identify NUDT15 as a potential biomarker for pancreatic cancer recurrence following surgery.

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