Translational Histopathology Lab
The Translational Histopathology Laboratory (THL) is based in the Old Road Campus Research Building next to the Churchill Hospital. It specialises in tissue handling and processing, including histochemistry, immunohistochemistry (IHC), multiplex Immunofluorescence (IF), RNAScope and computer-aided analysis of digitised slides. The lab is supported by funds from the NIHR/BRC and CRUK. It is led by Dr Sarah Blagden (Oncology) and Dr Alistair Easton (Pathology).
The THL provides support to biomedical research groups across the University as well as external, commercial, partners. It works in basic and translational research to develop IHC based assays on both mouse and human tissue. There is a strong focus on translational work, clinical trials and preclinical biomarker identification. We aim for the translation of research into clinically accredited and deployable, GCP compliant, validated assays.
The facility is available as a core service to any Oxford University or OUHFT based cancer researcher for the following:
Researcher and Laboratory Technician
View the overall structure and distribution of cells in your tissue samples with H&E staining
Observe antigens of interest in your tissue samples with single or double chromogenic IHC
Use HALO for faster and easier analysis of markers in your brightfield and fluorescent images
If you are interested in using any of the THL services please email email@example.com with the THL application form (downloaded here).
If you have any feedback on the website please let us know through the email above.
Picking Up Samples
If you are collecting or dropping off a sample at the THL lab, please go to reception at the address below and ask for extension 617057.
Old Road Campus Research Building,
The THL lab is supported by funding from: