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Immunocore approached Oxford cancer researchers in 2009 for advice on patient recruitment, regulatory development and trial design. They were advised on protocol development, regulatory approval and patient recruitment. We supported them through the MHRA special route that was implemented in response to the TeGenero scandal and delivered a phase -1 proof of concept package with built in early measures of efficacy, that lead to combination studies in multiple indications. At one stage the company was valued at $320M and work into their lead compounds mechanistic activity continues at Oxford.