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  • Adipose (fat) rich areas, such as those within breast and pancreas tissue, can show poor staining and are prone to lifting off the slide. TOMO slides are always recommended in these tissues.
  • Calcifications, which occur in tissues such as breast and serous tumours, can cause artefactual defects in tissue.
  • Tissues rich in endogenous peroxidases such as muscle and liver often show more non-specific staining.