| Antibody |
Target Description |
| AID |
Somatic hypermutation, gene conversion, and class-switch recombination of Ig genes |
| Alpha smooth muscle Actin |
Cytoskeleton marker: Muscle cells |
| Bcl-6 |
Activated and proliferating B cells in germinal centres |
| CAIX |
Hypoxia marker |
| Caspase3 |
Apoptosis marker |
| CD103 |
CD103 is expressed widely on intraepithelial lymphocyte (IEL) T cells (both αβ T cells and γδ T cells) and on some peripheral regulatory T cells (Tregs).It has also been reported on lamina propria T cells. A subset of dendritic cells in the gut mucosa and mesenteric lymph nodes, known as CD103 dendritic cells, also expresses this marker. |
| CD138 |
Plasma cells |
| CD146 |
Endothelial (cell lineage) marker |
| CD16 |
CD16, also known as FcγRIII, is a cluster of differentiation molecule found on the surface of natural killer cells, neutrophils, monocytes, and macrophages |
| CD19 |
B cells and follicular dendritic cells |
| CD2 |
CD2 (cluster of differentiation 2) is a cell adhesion molecule found on the surface of T cells and natural killer (NK) cells. It has also been called T-cell surface antigen T11/Leu-5, LFA-2, LFA-3 receptor, erythrocyte receptor and rosette receptor. |
| CD20 |
B cells |
| CD206 |
The mannose receptor (Cluster of Differentiation 206, CD206) is a C-type lectin primarily present on the surface of macrophages, immature dendritic cells and liver sinusoidal endothelial cells, but is also expressed on the surface of skin cells such as human dermal fibroblasts and keratinocytes. |
| CD21 |
Complement receptor type 2 (CR2), also known as complement C3d receptor, Epstein-Barr virus receptor, and CD21 (cluster of differentiation 21), B cells express CR2 receptors on their surfaces, allowing the complement system to play a role in B-cell activation and maturation |
| CD27 |
Memory B cells, some plasma cells, naïve and memory T cells and NK cells. A useful marker to distinguish certain T and B cell subets from each other. |
| CD3 |
T-cells |
| CD30 |
Reed-Sternberg cells |
| CD31 |
Vascular marker: Endothelial cells |
| CD32b |
Human CD32B (FcγRIIB), the low-affinity inhibitory receptor for IgG, is the predominant Fc receptor (FcR) present on B cells |
| CD34 |
Vascular marker: Endothelial cells |
| CD35 |
CD35 (cluster of differentiation 35) is a protein that in humans is encoded by the CR1 gene, The gene encodes a monomeric single-pass type I membrane glycoprotein found on erythrocytes, leukocytes, glomerular podocytes, hyalocytes, and splenic follicular dendritic cells |
| CD38 |
CD38 (cluster of differentiation 38), also known as cyclic ADP ribose hydrolase is a glycoprotein found on the surface of many immune cells (white blood cells), including CD4+, CD8+, B lymphocytes and natural killer cells. CD38 also functions in cell adhesion, signal transduction and calcium signaling. |
| CD4 |
T-Helper cells, monocyte/macrophages, granulocytes, thymocytes and Langerhans' cells |
| CD45 |
Protein tyrosine phosphatase, receptor type C. All differentiated hematopoietic cells (except erythrocytes and plasma cells). |
| CD5 |
T -cells |
| CD56 (NCAM) |
Neurons, astrocytes, Schwann cells, NK cells and a subset of activated T cells |
| CD68 |
Macrophages, monocyes, neutrophils, basophils and large lymphocytes, stimulated T cells and NK cells |
| CD8 |
Cytotoxic T-cells |
| CXCL14 |
(C-X-C motif chemokine ligand 14) Chemokine secreted by cancer associated fibroblasts (CAFs), Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes |
| CXCR5 |
B-cells. Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). |
| Cytokeratin 5 |
Identifying basal cells or myoepithelial cells in the breast and prostate |
| Cytokeratin 7 |
Cytoskeleton: Simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. |
| Desmin |
Cytoskeleton: Muscle cells (cardiac, skeletal and smooth) |
| E-Cadherin |
Epithelial marker (excluding neuronal epithelial): Intracellular junction marker |
| ENO1 |
(Enolase 1) Glycolysis. Cell surface receptor for plasminogen. Ubiquitously expressed in adult human tissues. |
| ER |
(Estrogen receptor) Nuclear hormone receptor |
| FOXP3 |
T regulatory cells |
| GFAP |
Astrocyte and neural stem cell marker |
| H3K36me3 |
Tri-methylation at the 36th lysine residue of the histone H3 protein associated with gene bodies and maintenance of genomic stability. |
| Hexon (Adenovirus) |
Major capsid protein (all 41 Adenovirus serotypes) |
| HR23B |
Nucleotide excision repair |
| Hypoxyprobe-1MAb1Anti-pimonidazole |
Hypoxia marker (pimonidazole administered) |
| Ki-67 |
Proliferating cells |
| LAMP3 |
Dendritic cells |
| LARP1 |
RNA-binding protein that regulates the translation of specific target mRNA species downstream of the mTORC1 complex, in function of growth signals and nutrient availability |
| MAP2 |
(Microtubule associated protein 2) Neurons |
| MECA-79 (PNAd) |
Vascular marker: High Endothelial Venule (HEV) |
| Melan A |
Melanocyte differentiation marker |
| MPO |
Monocytes, myeloid dentritic cells, neutrophils. Part of the host defense system of polymorphonuclear leukocytes. |
| Pan-Cytokeratin |
Cytoskeleton: Epithelial cells |
| PD-L1 |
Important checkpoint marker: Macrophages, T cells, B cells, NK cells and DCs |
| PD1 |
Important checkpoint marker: T cells and pro-B cells |
| Periostin |
Cell adhesion marker: Heparin |
| Podoplanin |
Lymphatic endothelial marker |
| PR |
(Progesterone receptor) Hormone receptor |
| Semaphorin 3A |
Axon guidance regulation marker: Meningeal fibroblasts |
| SQSTM-p62 |
(Sequestosome-1 is a protein is encoded by SQSTM1 gene also known as the ubiquitin-binding protein p62) autophagosome cargo protein, autophagosome marker: ubiquitously expressed in tissue. |
| TIA1 |
TIA1 cytotoxic granule associated RNA binding protein that possesses nucleolytic activity against cytotoxic lymphocyte (CTL) target cells. |
| TNFR1 |
(Tumor necrosis factor receptor 1): cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation: mainly secreted by macrophages |
| VEGF |
(Vascular endothelial growth factor) Angiogenesis, tumour angiogenesis and vasculogenesis marker |
| VEGFR2 |
(Vascular endothelial growth factor receptor 2) accounts for most of the mitogenic and chemotactic effects of VEGF: Cell culture supernatant, Serum, Hep Plasma, EDTA Plasma, Cit plasma |