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Siu Shing Wong

DPhil, Sir William Dunn School of Pathology


Project: Crosstalk between the tumour suppressor p53 and inflammation pathways

Siu Shing Wong earned his BSc in Biochemistry from the Chinese University of Hong Kong (2012-2016). During his undergraduate study, he visited Taiwan thrice to work on ubiquitin and neural development in Ruey-hwa Chen’s lab. He has now become a member of Jordan Raff’s team as a 4-year DPhil student, working on centriole dynamics in Drosophila embryo.

What’s your current research and how could it impact patients?

One way to create a cancer cell is by abnormal cell division which results in DNA damage. The centrosome has been a major player in the process, found either amplified or enlarged in cancer. My project seeks to understand the size control mechanism of centrosomes which will shed light on this elusive phenomenon in disease. Conversely, we may be able to block cancer progression by limiting centrosome size or number.

What does a typical day look like for you?

I think of myself as a paparazzi photographer who take tons of images regarding the secret life of the centrosome so as to give the scientific community an unprecedented understanding of it. In simple words, it’s hectic yet fulfilling.

And finally, what do you do outside of your studies?

I enjoying reading and discussing emerging technologies with friends. I like to play Go. I also play violin together with friends.