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Early-Stage Cancer Biology provides a fundamental understanding of how cancer begins and develops. Many studies aim to identify the differences between cellular processes in healthy vs. cancer cells. However, the development of cancer is dynamic and the study of these processes over time (or through intermediate states) is required to capture the earliest indicators of cancer, which could be hard to spot while only investigating established or late-stage tumours. This approach taken by Oxford researchers will enable a new window of opportunity for early detection.