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  • Challenge: Predicting progression

Over 22,000 endoscopies are performed at OUH every year. Oxford researchers are offering all patients undergoing an endoscopic test, including those undergoing surveillance for precancerous gastrointestinal conditions, the opportunity to participate in cutting edge translational medical research as part of their required clinical investigation. Oxford Cancer is linking the resulting large research datasets with other health records and outputs from tissue analysis and model systems such as patient-derived organoids to identify determinants of progression (or non-progression) to gastrointestinal cancers from high-risk precancerous conditions, such as Barrett’s oesophagus and colorectal polyps.