Optimising TIME for radiotherapy response
- Collaborators: Richard Bryant, Eileen Parkes, Ian Mills
- Challenge: Expanding the immuno-oncology footprint
Mapping of TIME evolution will be applied to define the STING-mediated immune response to ionising radiation. By identifying the mechanisms responsible for the formation and establishment of radioresistant clones Oxford researchers are establishing how modulation of the STING pathway can enhance the efficacy of radiation therapy.