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A new editorial published in the British Journal of General Practice examines how recent research presents an opportunity to refresh how risk thresholds are applied in national primary care cancer referral guidelines. This article was written by Brian Nicholson, Associate Professor in the Nuffield Department of Primary Care Health Sciences, in collaboration with academic thought-leaders from across the UK and CRUK.

Around two thirds of patients with cancer diagnosed in England first present to primary care so encouraging timely referral of those with signs and symptoms of possible cancer is crucial to improve patient outcomes.

Cancer referral guidelines play a key role in supporting healthcare professionals to identify individuals with suspected cancer in a timely and consistent manner. Most UK guidelines use risk thresholds to determine which patients warrant urgent suspected cancer investigation or referral. These thresholds are based on the positive predictive value (PPV) of signs and symptoms alone or in combination.

Read the full article in the British Journal of General Practice

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Oxford Oncology at ESMO 2025

The European Society of Medical Oncology (ESMO) Annual Congress took place on 17th-21st October, showcasing the latest advances and insights from the global oncology community. As Europe’s largest oncology meeting, ESMO brings together thousands of researchers, clinicians, and industry leaders for an exchange of cutting-edge research and clinical innovation. Members of the Department of Oncology were in Berlin to present their research, chair sessions, and network with collaborators from across Europe and beyond. Below are some of the highlights from our department’s contributions to ESMO 2025.