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« Back to NewsThe latest news, stories and exciting findings from across the Oxford cancer research community
Researchers describe how cancer cells can defend themselves from the consequences of certain genetic defects
20 September 2022
Swietach Group scientists have identified a rescue mechanism that allows cancers to overcome the consequences of inactivating mutations in critically important genes
Genetic mapping of tumours reveals how cancers grow
11 August 2022
Researchers from the University of Oxford, KTH Royal Institute of Technology, Science for Life Laboratory, and the Karolinska Institutet, Solna, Sweden, have found that individual prostate tumours contain a previously unknown range of genetic variation.
Genetic testing could reduce adverse effects and hospital costs of a widely used chemotherapy
28 April 2022
Testing for DPYD gene variants could be used to mitigate the side-effects of fluoropyrimidine-based chemotherapy
DNA link could unlock mystery of cancer patients ‘wasting away’
13 February 2022
New research by Oxford researchers into sudden weight loss finds a possible cause of cachexia (sudden weight loss & muscle wasting) in cancer patients and Cockayne syndrome in children.
How Oxford has shaped cancer science
4 February 2022
As part of World Cancer Day 2022 we are diving into 10 of Oxford’s most impactful historical and modern contributions to the field of cancer science and treatment. Read more about what Oxford researchers have done to shape this ever-important area of medical science.
Eileen Parkes awarded Wellcome Clinical Research Career Development Fellowship
10 January 2022
Eileen will investigate the expression of genetic instability and how it shapes the immune microenvironment of oesophageal cancers.
Dr Heba Sailem wins international award for work on cancer gene functions
1 December 2021
The Swiss Institute of Bioinformatics has recognised the work of research fellow Dr Heba Sailem with the Early Bioinformatician Award.
New model for infant leukaemia announced
28 November 2021
The breakthrough could lead to development of new treatments for infant Acute Lymphoblastic Leukaemia.
Mechanism behind repair of cancer-inducing mutations discovered
28 July 2021
New research from Ross Chapman’s lab has discovered the precise mechanism behind how the BRCA1 protein detects and engages with DNA breaks in the genome, helping to prevent the development of breast and ovarian cancers.
The next step in personalised cancer medicine
6 July 2021
Botnar Research Centre researchers have developed standalone long-read sequencing of single cells technology that could open new avenues into the causes of diseases like cancer.
Oxford Cancer welcomes Professor Stefan Constantinescu
5 July 2021
Professor Stefan Constantinescu joins Ludwig Oxford to expand his research programme in cancer epigenetics.
Understanding mutation progression to detect ovarian cancer earlier
7 May 2021
Nina Wietek from the Ahmed lab is investigating fallopian tube tissue to see what we can understand about precancerous mutations in the tissue from which ovarian cancers develops.
New method for cost-effective genome-wide DNA methylation analysis
28 April 2021
Dr Chunxiao Song’s team build on its TAPS method to develop an alternative to costly whole-genome sequencing for the detection of DNA methylation.
Registration open for Cancer Early Detection and Epigenetics Symposium
15 March 2021
Join us and our co-hosts for this free virtual event on 28-29th April 2021 to hear the latest developments from international leaders in these fields
Improving immunotherapy through epigenetics
12 March 2021
Professor Yang Shi’s group uses combination therapy to eradicate tumours that previously responded poorly to immunotherapy
Developing a system to simultaneously detect genetic and epigenetic information
2 March 2021
Dr Benjamin Schuster-Böckler wins funding to develop algorithms that can identify both genetic variation and DNA methylation from the same sequencing data, with applications in biomedical research and detection of diseases such as cancer.
Understanding how inherited and acquired mutations interact to affect cancer
18 February 2021
Development fund awardee Gareth Bond is investigating how different types of genetic mutations cooperate to influence cancer risk, progression and response to therapy
New sequencing methods for distinguishing DNA modifications
27 January 2021
Dr Chunxiao Song’s team have expanded their suite of bisulphite-free DNA modification sequencing methods to specifically and directly detect each of the four modifications made to the DNA base cytosine
Potential of DNA-based blood tests for detecting pancreatic cancer earlier
11 December 2020
Dr Shivan Sivakumar and colleagues evaluate the current progress and future potential in using genetic and epigenetic methods for detecting pancreatic cancer DNA in the blood.
Oxford Cancer alumni’s biotech success
11 November 2020
Scenic Biotech, co-founded by former Ludwig Oxford Cancer group leader Sebastian Nijman, collaborates with Roche group member Genentech in a $375m deal