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« Back to NewsThe latest news, stories and exciting findings from across the Oxford cancer research community
Researchers describe how cancer cells can defend themselves from the consequences of certain genetic defects
20 September 2022
Swietach Group scientists have identified a rescue mechanism that allows cancers to overcome the consequences of inactivating mutations in critically important genes
Tool to detect cancer stem cell make-up in intestinal tumours
5 August 2022
The Leedham lab have developed a new tool that assesses the relative enrichment of two main types of cancer stem cells in colorectal cancer, which may help to guide therapy selection in the future.
How Oxford has shaped cancer science
4 February 2022
As part of World Cancer Day 2022 we are diving into 10 of Oxford’s most impactful historical and modern contributions to the field of cancer science and treatment. Read more about what Oxford researchers have done to shape this ever-important area of medical science.
Eileen Parkes awarded Wellcome Clinical Research Career Development Fellowship
10 January 2022
Eileen will investigate the expression of genetic instability and how it shapes the immune microenvironment of oesophageal cancers.
Study reveals ‘stop-eating’ response to DNA damage
25 November 2021
A new study sheds light on the mechanism by which DNA damage suppresses appetite, a finding with implications for understanding the appetite lowering side-effects of chemotherapy.
Changes in blood cell production over the human lifetime may hold clues to patterns of disease
16 September 2021
A new paper published this week in Cell Reports reveals that changes in the gene expression of blood stem cells occur across the human lifetime; an important step in the understanding and treatment of blood cancers.
Mechanism behind repair of cancer-inducing mutations discovered
28 July 2021
New research from Ross Chapman’s lab has discovered the precise mechanism behind how the BRCA1 protein detects and engages with DNA breaks in the genome, helping to prevent the development of breast and ovarian cancers.
Protein structure solution paves way for improved anti-cancer drugs
16 July 2021
A new study from the Newstead group at the Department of Biochemistry has solved the structure of the human folate transporter, paving the way for improved anticancer drugs.
The next step in personalised cancer medicine
6 July 2021
Botnar Research Centre researchers have developed standalone long-read sequencing of single cells technology that could open new avenues into the causes of diseases like cancer.
Two clinical academic research partnerships awarded to Oxford researchers
22 June 2021
Congratulations to Dr Karthik Ramasamy & Dr John Jacob on their CARP awards from the Medical Research Council. Find more about their work that is being funded.
The nervous system & cancer progression
4 June 2021
Using her new CRUK Oxford Centre Development Fund award, Dr Linna Zhou will investigate the role of the nervous system in cancer progression using engineered gastrointestinal tissues.
Artificial intelligence tool for streamlining pathology workflow
26 May 2021
A multidisciplinary team in Oxford has developed an algorithm for automated requesting of additional investigation in diagnostically uncertain prostate biopsies.
New study investigates how growth factors in our gut could initiate cancer
5 May 2021
Dr Francesco Boccellato is investigating the mechanisms of tissue regulation in the healthy stomach and in a pre-cancerous condition known as atrophic gastritis. This may help to identify those who may have cancer, as well as find new ways to prevent cancer from progressing
DeLIVER clinical research study underway as recruitment opens
23 March 2021
The DELPHI project, one of three clinical studies within the DeLIVER programme for early detection of liver cancer, has started recruiting patients.
Finding extracellular vesicle biomarkers for oesophageal cancer early detection
22 February 2021
Prof Deborah Goberdhan’s lab is investigating extracellular vesicles and the proteins they express as potential biomarkers for the progression from Barrett’s Oesophagus to oesophageal cancer
Reprogramming tumour cells using an antimalarial drug
17 February 2021
Results from the ATOM clinical trial at the University of Oxford have shown that the anti-malarial drug Atovaquone can reduce very low oxygen tumour environments. This has the potential to make cancers behave less aggressively and to improve the impact of everyday cancer treatments.
Understanding how cancer arises from infected tissue
11 February 2021
Dr Francesco Boccellato is investigating the mechanisms behind the pre-cancerous condition known as atrophic gastritis. This may help to identify those who may have cancer, as well as find new ways to prevent cancer from progressing.
Following the cancer metabolomic breadcrumb trail
1 February 2021
By analysing the metabolic molecules that tumour cells leave behind, Dr James Larkin is investigating the applications of metabolomics in the early detection of many cancers.
New form of gift wrap drives male reproductive success
26 January 2021
A new cell communication mechanism that's been identified could have implications for breast cancer and understanding its pathology
New hydrogel technology has promise in breast cancer modelling
26 October 2020
A new hydrogel technology from the Farnie group has provided cancer researchers with a new way to faithfully model breast tumours and discover new therapeutic targets