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The collective force of cancer research, outreach and care across the city of Oxford, translating discoveries into better care for cancer patients.

International Day of Women and Girls in Science: In conversation with Lena Duma

To mark International Day of Women and Girls in Science 2026, we interviewed several of our DPhil in Cancer Science students and alumnae to discuss what motivated them to pursue careers in cancer research. Hear from fourth-year Fundamental Scientist, Lena Duma, whose work in the Sir William Dunn School of Pathology focuses on a DNA repair system in cells in order to better understand how certain cancer treatments work.

International Day of Women and Girls in Science: In conversation with Hannah Baillie

To mark International Day of Women and Girls in Science 2026, we interviewed several of our DPhil in Cancer Science students and alumnae to discuss what motivated them to pursue careers in cancer research. Hear from third-year Fundamental Scientist, Hannah Baillie, who works in the Department of Chemistry investigating acute myeloid leukaemia, an aggressive type of blood cancer.

Treatment of tumours with sound: new high-intensity focused ultrasound machine installed

A new state-of-the-art high-intensity focused ultrasound (HIFU) machine has been installed at the Churchill Hospital, giving Oxford University Hospitals (OUH) cancer patients access to the latest in this innovative technology.

New clinical study launched examining the role of insulin in breast cancer treatment response

A new clinical study has launched to investigate whether insulin levels influence how women with the most common type of breast cancer respond to treatment.

Is now the time to rethink risk thresholds in cancer referral guidelines?

A new editorial published in the British Journal of General Practice examines how recent research presents an opportunity to refresh how risk thresholds are applied in national primary care cancer referral guidelines. This article was written by Brian Nicholson, Associate Professor in the Nuffield Department of Primary Care Health Sciences, in collaboration with academic thought-leaders from across the UK and CRUK.

Oxford Oncology at ESMO 2025

The European Society of Medical Oncology (ESMO) Annual Congress took place on 17th-21st October, showcasing the latest advances and insights from the global oncology community. As Europe’s largest oncology meeting, ESMO brings together thousands of researchers, clinicians, and industry leaders for an exchange of cutting-edge research and clinical innovation. Members of the Department of Oncology were in Berlin to present their research, chair sessions, and network with collaborators from across Europe and beyond. Below are some of the highlights from our department’s contributions to ESMO 2025.

Oxford Cancer Announces 2025 CRIS Cancer Clinical Career Fellows

Oxford Cancer, together with the CRIS Cancer Foundation, is delighted to announce the appointment of the 2025 CRIS Cancer Postdoctoral Clinical Fellows: Dr Rebecca Ling and Dr Casmir Turnquist. Both Fellows will lead on two distinct projects focused on childhood cancer.

Dr Peter Wan Awarded Pancreatic Cancer UK Fellowship to Develop New Immunotherapy for Pancreatic Cancer

Dr Peter Kok-Ting Wan, PhD, postdoctoral researcher at the Department of Oncology, has been awarded a prestigious fellowship from Pancreatic Cancer UK to develop a new immunotherapy for pancreatic cancer, which has the lowest survival rate of any common cancer

Iron Levels Found to Play a Key Role in FLASH Radiotherapy’s Tissue-Sparing Effect

Researchers in the Department of Oncology have uncovered new insights into how FLASH radiation therapy (RT) kills cancer cells while minimising damage to healthy tissues. The study, led by Dr Ejung Moon in collaboration with Dr Kristoffer Petersson, has demonstrated that FLASH RT induces iron-dependent cell death in tumour cells but not in healthy cells, which may contribute to its tissue sparing effect. Notably, tissue iron levels were shown to critically influence this process, opening new avenues of investigation into which cancer types may benefit most from this promising therapeutic technique.

Scientists reveal how cells repair toxic DNA damage linked to cancer and premature ageing

Researchers at the University of Oxford and Nanyang Technological University, Singapore have uncovered the mechanism by which cells identify and repair a highly toxic form of DNA damage that causes cancer, neurodegeneration, and premature ageing.

Study finds potential path to treatment for an aggressive form of leukaemia

In a collaborative new study, researchers at Ludwig Cancer Research Oxford have identified a potential new therapeutic target in blast phase myeloproliferative neoplasm, a particularly aggressive and hard-to-treat form of leukaemia.

The stellar mission taking on cellular plasticity in bowel cancer

Backed by £5.5m of funding from CRUK and its partners, the hugely ambitious CRC-STARS programme - which is co-lead by Professor Simon Leedham in the Nuffeild Department of Medicine - aims to revolutionise how bowel cancer is treated.

New research reveals druggable target arising from chromosomal rearrangement in aggressive leukaemia

Researchers at the University of Oxford have uncovered a potential new therapeutic target in a particularly aggressive and hard-to-treat form of leukaemia.

New Study Finds Common Virus May Improve Skin Cancer Treatment Outcomes

A new study led by the University of Oxford has revealed that a common and usually harmless virus may positively influence how skin cancer patients respond to current treatments.

Pancreatic cancer immune map provides clues for precision treatment targeting

New research - published today in Nature Communications - shows why there are differences in prognosis between different pancreatic tumours and identifies potential avenues for improved treatment approaches.

Predicting Response to Rectal Cancer Treatment through the S:CORT consortium

Recent research from the S:CORT team spanning three publications has identified key biomarkers and treatment strategies that predict and enhance effectiveness of radiotherapy in rectal cancer treatment.

Researchers develop new tool to better predict AML outcomes in older patients

In a study published in the Journal of Clinical Oncology, an international research team has used machine learning to improve risk stratification for patients over 60 diagnosed with acute myeloid leukaemia, an aggressive type of blood cancer.

Oxford Cancer: 5 minutes with Professor Dame Molly Stevens

Professor Dame Molly Stevens is John Black Professor of Bionanoscience in the Department of Physiology, Anatomy and Genetics and the Institute of Biomedical Engineering. She recently moved her lab from Imperial College London to the University of Oxford and the Kavli Institute for nanoscience discovery, and she is joining the Oxford Cancer community.

OCION Funding Scheme: In conversation with David Church and Luciana Gneo

The mission of the Oxford Cancer Immuno-Oncology Network (OCION) Funding Scheme is to pump-prime innovative Oxford-based immuno-oncology research and build capacity in cancer immunology. We sat down with 2023 awardees, David Church and Luciana Gneo, to discuss what research the fund will enable them to carry out.

Research team receives $25m Cancer Grand Challenges award

A global, interdisciplinary team of researchers has been selected to receive a Cancer Grand Challenges award of up to $25m over five years to tackle the solid tumours in children challenge.

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