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The collective force of cancer research, outreach and care across the city of Oxford, translating discoveries into better care for cancer patients.

In situ multi-modal characterization of pancreatic cancer reveals tumor cell identity as a defining factor of the surrounding microenvironment.

Lyubetskaya A. et al, (2026), Cell Rep, 45

Off-the-shelf dual CAR-iNKT cell immunotherapy eradicates medullary and leptomeningeal high-risk KMT2A-rearranged leukemia.

Ren H. et al, (2026), Blood, 147, 180 - 196

Stem-like CD8+ T cells preserve HBV-specific responses in HBV/HIV co-infection.

Preechanukul A. et al, (2025), Gut

Genetic determinants of monocyte splicing are enriched for disease susceptibility loci.

Nassiri I. et al, (2025), Nat Commun, 16

Self-Reactive B Cells in Artery Tertiary Lymphoid Organs Encode Pathogenic High Affinity Autoantibody in Atherosclerosis

Zhang C. et al, (2025)

SpatioEv: Spatial evolution of protein and morphological features reveals development dynamics of cells and spatial neighbourhoods

Wu S. et al, (2025)

CMV serostatus is associated with improved survival and delayed toxicity onset following anti-PD-1 checkpoint blockade.

Milotay G. et al, (2025), Nat Med, 31, 2350 - 2364

Defective peripheral B cell tolerance leads to dysregulated B cell responses in Fibromyalgia Syndrome

Bashford-Rogers R. et al, (2025)

Permissive central tolerance plus defective peripheral checkpoints license pathogenic memory B cells in CASPR2-antibody encephalitis.

Sun B. et al, (2025), Sci Adv, 11

Disease-specific B cell clones are shared between patients with Crohn's disease.

Kotagiri P. et al, (2025), Nat Commun, 16

Stem-like CD8+ T cells preserve HBV-specific responses in HBV/HIV co-infection.

Preechanukul J. et al, (2025)

Distinct immune cell infiltration patterns in pancreatic ductal adenocarcinoma (PDAC) exhibit divergent immune cell selection and immunosuppressive mechanisms.

Sivakumar S. et al, (2025), Nat Commun, 16

Bi-specific CAR-iNKT cell immunotherapy for high-risk KMT2A-rearranged leukemia outperforms CAR-T in an NKG2D-dependent manner and eradicates leptomeningeal disease

Ren H. et al, (2025)

Permissive central tolerance plus defective peripheral checkpoints licence pathogenic memory B cells in CASPR2-antibody encephalitis.

Sun B. et al, (2025)

Tissue-resident natural killer cells support survival in pancreatic cancer through promotion of cDC1-CD8 T activity.

Go S. et al, (2024), Elife, 13

Tissue-resident natural killer cells support survival in pancreatic cancer through promotion of cDC1-CD8 T activity

Go S. et al, (2024), eLife, 13

Tumour purity assessment with deep learning in colorectal cancer and impact on molecular analysis.

Schoenpflug LA. et al, (2024), The Journal of pathology

Cytomegalovirus infection protects against metastatic melanoma and modulates oncological outcome and toxicity to checkpoint immunotherapy

Milotay G. et al, (2024)

Computational Workflow to Design Novel Vaccine Candidates and Small-Molecule Therapeutics for Schistosomiasis.

Balogun EO. et al, (2024), Pathogens, 13

HIV/HBV coinfection remodels the immune landscape and natural killer cell ADCC functional responses.

Sun B. et al, (2024), Hepatology, 80, 649 - 663

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